Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729466 | 0.87 | SMN1; SMN2 (0.38) | ALDH1A1NNMTNCOA1NCOA3HTT | |
| SCHEMBL5482060 | 0.83 | NCOA1 (0.38) | ALDH1A1NNMTNCOA1NCOA3HTT | |
| SCHEMBL697442 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1NNMTKDM4EMEN1KMT2A | |
| SCHEMBL9755787 | 0.79 | KDM4E (0.42) | ALDH1A1NCOA1NCOA3HTTKDM4E | |
| SCHEMBL7594740 | 0.77 | NNMT (0.40) | ALDH1A1NNMTNCOA1NCOA3HTT | |
| SCHEMBL8531143 | 0.74 | SMN1; SMN2 (0.35) | ALDH1A1NNMTKDM4EMEN1KMT2A | |
| SCHEMBL4951717 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1NNMTKDM4EIKBKBSMN1; SMN2 | |
| SCHEMBL3828018 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1NNMTKDM4EIKBKBSMN1; SMN2 | |
| SCHEMBL6588836 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1NNMTNCOA1NCOA3HTT | |
| SCHEMBL7414268 | 0.74 | KDM4E (0.34) | ALDH1A1NNMTNCOA1NCOA3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981713-B | Preparation method and application of 4-hydroxy emodin | 沈阳药科大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-110981713-A | Preparation method and application of 4-hydroxy emodin | 沈阳药科大学 | 2020-04-10 | — | — | CN | disclosed |