Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393333 | 0.83 | ALDH1A1 (0.37) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL13729466 | 0.80 | SMN1; SMN2 (0.38) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL7594740 | 0.79 | NNMT (0.40) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL27734973 | 0.79 | NCOA1 (0.35) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL9755787 | 0.78 | KDM4E (0.42) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL28975003 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6588836 | 0.76 | SMN1; SMN2 (0.38) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL7414268 | 0.76 | KDM4E (0.34) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| SCHEMBL28925024 | 0.76 | NNMT (0.40) | NCOA1NCOA3ALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL28553424 | 0.75 | NNMT (0.39) | NCOA1NCOA3ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254906-A1 | Method of Administration of Dopamine Receptor Agonists | DARPHARMA, INC. (US) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254906-A1 | Method of Administration of Dopamine Receptor Agonists | ADRA1D, DRD2, CHRM3 | NCOA1 3320/4885NCOA3 2801/4885ALDH1A1 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.