Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527024 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL27856953 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7792129 | 0.83 | LCK (0.42) | KDM4EALDH1A1HTTTSHRAPOBEC3A | |
| SCHEMBL1260575 | 0.81 | HMGCR (0.41) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28393333 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL5482060 | 0.78 | NCOA1 (0.38) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28921381 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL3342389 | 0.77 | HMGCR (0.50) | KDM4EALDH1A1HTTKMT2AHMGCR | |
| SCHEMBL7799274 | 0.77 | PTPN1 (0.41) | KDM4EALDH1A1HTTMEN1KMT2A | |
| Acetic Acid SCHEMBL5925567 | 0.76 | HTR4 (0.51) | KDM4EALDH1A1HTTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |