Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497826 | 0.81 | MEN1 (0.71) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21443485 | 0.81 | AURKA (0.62) | RAB9ASMN1; SMN2AURKANPC1CDK5 | |
| SCHEMBL17364440 | 0.80 | TSHR (0.70) | RAB9AMAPTMEN1KMT2ATSHR | |
| SCHEMBL7128152 | 0.78 | HPGD (0.66) | RAB9AMAPTMEN1KMT2ATSHR | |
| SCHEMBL9186456 | 0.78 | RAB9A (0.61) | RAB9AMAPTMEN1KMT2ATSHR | |
| SCHEMBL5419878 | 0.78 | GSK3B (0.61) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5996779 | 0.77 | CYP11B1 (0.54) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29953075 | 0.76 | AURKA (0.54) | RAB9AMAPTSMN1; SMN2AURKANPC1 | |
| SCHEMBL3949026 | 0.76 | NFKB1 (0.61) | SMN1; SMN2AURKACDK5CDK5R1CCNA2 | |
| SCHEMBL2285411 | 0.75 | ABL1 (0.69) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108148005-B | O-aminophenol derivatives and preparation method thereof | 暨南大学 | 2020-04-14 | — | — | CN | disclosed |