Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.85 |
| ▸ | GABRD | O14764 | 3/20 | 0.85 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.85 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.85 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.85 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.85 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.85 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.85 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.85 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.85 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.85 |
| ▸ | GABRE | P78334 | 3/20 | 0.85 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.85 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.85 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.85 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.85 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.53 |
| ▸ | KDM5C | P41229 | 6/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220538 | 0.92 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30705741 | 0.92 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL22797869 | 0.90 | GABRP (0.96) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Nitrous Acid SCHEMBL28381983 | 0.78 | KDM4C (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Nitrous Acid SCHEMBL28404954 | 0.78 | KDM4C (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Nitrous Acid SCHEMBL29072872 | 0.78 | KDM4C (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL446809 | 0.76 | GABRP (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28394531 | 0.75 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19586492 | 0.75 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1159738 | 0.75 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909133-B | Substituted 1-amino-1H-imidazole-5-carboxamides as inhibitors of brunauer tyrosine kinase | 河南知微生物医药有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113874372-A | Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi | PI工业有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-107105667-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-111909133-A | Substituted 1-amino-1H-imidazole-5-carboxamides as brunauer tyrosine kinase inhibitors | 河南师范大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-111132967-A | Cyclic olefin substituted heteroaromatic ring compound and application thereof | 和记黄埔医药（上海）有限公司 | 2020-05-08 | — | — | CN | disclosed |