Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.53 |
| ▸ | KDM5C | P41229 | 7/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.53 |
| ▸ | KDM4A | O75164 | 5/20 | 0.53 |
| ▸ | KDM6B | O15054 | 4/20 | 0.53 |
| ▸ | KDM5A | P29375 | 4/20 | 0.53 |
| ▸ | ASPH | Q12797 | 2/20 | 0.53 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118817 | 0.92 | KDM4C (0.61) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| SCHEMBL29957382 | 0.92 | KDM4C (0.61) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Hydrochloric Acid SCHEMBL28045024 | 0.90 | KDM4C (0.59) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Methacrylic Acid SCHEMBL11898560 | 0.81 | KDM4C (0.49) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL28381983 | 0.78 | KDM4C (0.53) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL28404954 | 0.78 | KDM4C (0.53) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL28394532 | 0.78 | GABRP (0.85) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL28422704 | 0.77 | KDM4C (0.49) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL28883192 | 0.77 | KDM4C (0.49) | KDM4CKDM5CKDM5BKDM4EKDM2A | |
| Nitrous Acid SCHEMBL29134658 | 0.77 | KDM4C (0.57) | KDM4CKDM5CKDM5BKDM4EKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | disclosed |