Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MYOC | Q99972 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24236984 | 0.84 | KDM4E (0.71) | MEN1KMT2AMAPTAPEX1NPC1 | |
| SCHEMBL1177730 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTAPEX1NPC1 | |
| SCHEMBL6302157 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTAPEX1NPC1 | |
| SCHEMBL6295847 | 0.82 | MEN1 (0.60) | MEN1KMT2AMAPTAPEX1NPC1 | |
| SCHEMBL28396223 | 0.79 | CASP3 (0.65) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL6302417 | 0.79 | MEN1 (0.89) | MEN1KMT2AMAPTAPEX1NPC1 | |
| SCHEMBL28397382 | 0.78 | CASP3 (0.67) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL28394913 | 0.78 | HPGD (0.58) | MEN1KMT2AMAPTCASP3CA1 | |
| SCHEMBL29664268 | 0.78 | HPGD (0.58) | MEN1KMT2AMAPTCASP3CA1 | |
| SCHEMBL28062212 | 0.78 | RAB9A (0.66) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456215-A | Contain fluorenes or Fluorenone structure function diamine monomer and its synthetic method and application with high flatness | 湖南工业大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-105693539-B | Diamine monomer containing fluorene or fluorenone structure and having high planarity as well as synthesis method and application thereof | 湖南工业大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-105693539-A | Diamine monomer containing fluorene or fluorenone structure and having high planarity as well as synthesis method and application thereof | 湖南工业大学 | 2016-06-22 | — | — | CN | disclosed |