Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418479 | 0.83 | LMNA (0.34) | ADRB2PDE2ATSHRMAPK1HIF1A | |
| SCHEMBL29888904 | 0.81 | SLC6A4 (0.33) | ADRB2PDE2ATSHRMAPK1HIF1A | |
| SCHEMBL13778645 | 0.80 | SLC6A2 (0.37) | PDE2ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL14373872 | 0.80 | SLC6A2 (0.37) | PDE2ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL13778630 | 0.80 | SLC6A2 (0.37) | PDE2ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL28118844 | 0.80 | MIF (0.53) | PDE2ATDP1MIFAOC3LMNA | |
| SCHEMBL31172465 | 0.80 | BRD4 (0.41) | TSHRSLC6A4SLC6A3LMNABRD4 | |
| SCHEMBL14373887 | 0.77 | PDE2A (0.37) | PDE2A | |
| SCHEMBL16166542 | 0.76 | PDE2A (0.59) | ADRB2PDE2ATSHRMAPK1HIF1A | |
| SCHEMBL19479213 | 0.76 | ADRB2 (0.40) | ADRB2TSHRMAPK1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759564-B | Triazole pyridine formyl glycine compound, method and medical application thereof | 中国药科大学 | 2020-05-22 | — | — | CN | disclosed |