Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.81 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.81 |
| ▸ | TDP2 | O95551 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | CASP9 | P55211 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.63 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891502 | 0.90 | AHR (0.70) | AHRPDK2TDP2CASP3CASP7 | |
| SCHEMBL2825070 | 0.90 | AHR (0.70) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL29358826 | 0.90 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL19504 | 0.90 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL1144643 | 0.90 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| Hydrochloric Acid SCHEMBL6391264 | 0.89 | AHR (0.68) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL5502064 | 0.88 | AHR (0.95) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL8866524 | 0.88 | AHR (0.95) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL5624006 | 0.88 | AHR (0.95) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL1236964 | 0.88 | AHR (0.95) | AHRPDK2TDP2CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790771-A | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | disclosed |