Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.70 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.70 |
| ▸ | TDP2 | O95551 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | CASP9 | P55211 | 1/20 | 0.66 |
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.66 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 4/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825070 | 1.00 | AHR (0.70) | AHRPDK2TDP2CASP3CASP7 | |
| Hydrochloric Acid SCHEMBL6391264 | 0.98 | AHR (0.68) | AHRPDK2TDP2CASP3CASP7 | |
| Fluorene SCHEMBL28396879 | 0.90 | AHR (0.81) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL19504 | 0.83 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL1144643 | 0.83 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL29358826 | 0.83 | AHR (1.00) | AHRPDK2TDP2CASP3CASP7 | |
| SCHEMBL4994383 | 0.81 | GRIA1 (0.56) | AHRPDK2TDP2CASP3CASP7 | |
| SCHEMBL4413360 | 0.81 | CCNB2 (0.54) | AHRPDK2TDP2CASP3CASP7 | |
| SCHEMBL6312601 | 0.81 | CCNB2 (0.54) | AHRPDK2TDP2CASP3CASP7 | |
| Oxindole SCHEMBL4720301 | 0.81 | AHR (0.95) | AHRPDK2TDP2CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994397-A | Trispecific binding molecules directed against BCMA and uses thereof | 诺华股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-114173810-B | Trispecific binding molecules directed against BCMA and uses thereof | 诺华股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118459594-A | Binding molecules to BCMA and uses thereof | 诺华股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-112384531-B | Binding molecules to BCMA and uses thereof | 诺华股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11981929-B2 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | JANSSEN BIOTECH, INC. (US) | 2024-05-14 | — | — | US | disclosed |