SCHEMBL28397254

SCHEMBL28397254

CCCCCC/C=C\COC(=O)CCCCCCCC(CCCCCCCC(=O)O)NC(=O)CCCN(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.50
PLA2G10 O15496 1/20 0.47
EPHX2 P34913 5/20 0.46
SLC6A5 Q9Y345 1/20 0.45
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
MAPT P10636 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10081428 0.96 DEGS1 (0.47) PLA2G2CSLC6A5FAAHKMT2A
SCHEMBL16290467 0.96 DEGS1 (0.47) PLA2G2CSLC6A5FAAHKMT2A
SCHEMBL28397912 0.95 PLA2G2C (0.48) PLA2G2CPLA2G10EPHX2TERTPTPN1
SCHEMBL16290473 0.94 DEGS1 (0.47) PLA2G2CSLC6A5FAAHKMT2A
SCHEMBL14879413 0.94 DEGS1 (0.47) PLA2G2CSLC6A5FAAHKMT2A
SCHEMBL16099935 0.91 DNM1 (0.46) PLA2G2CSLC6A5FAAH
SCHEMBL14879498 0.91 DNM1 (0.46) PLA2G2CSLC6A5FAAH
SCHEMBL30381906 0.85 PRKCA (0.53) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL17379642 0.85 PRKCA (0.53) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL10081362 0.84 DNM1 (0.46) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107266391-B Amine cationic lipids and uses thereof 迪克纳制药公司 2020-04-17 CN disclosed