SCHEMBL14879413

SCHEMBL14879413

CCCCCC/C=C\COC(=O)CCCCCCCC(CCCCCCCC(=O)OC/C=C\CCCCCC)NC(=O)CCCCN(C)C

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.47
LPAR3 Q9UBY5 2/20 0.46
PLA2G4A P47712 1/20 0.46
SLC6A5 Q9Y345 1/20 0.46
PLA2G2C Q5R387 1/20 0.45
DNM1 Q05193 1/20 0.45
DGKA P23743 1/20 0.45
CETP P11597 3/20 0.44
FAAH O00519 1/20 0.44
PRKCE Q02156 1/20 0.43
PRKCQ Q04759 1/20 0.43
PRKCD Q05655 1/20 0.43
THRB P10828 1/20 0.43
PRKCA P17252 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16290473 1.00 DEGS1 (0.47) DEGS1LPAR3PLA2G4ASLC6A5PLA2G2C
SCHEMBL16290467 0.98 DEGS1 (0.47) DEGS1LPAR3PLA2G4ASLC6A5PLA2G2C
SCHEMBL10081428 0.98 DEGS1 (0.47) DEGS1LPAR3PLA2G4ASLC6A5PLA2G2C
SCHEMBL14879498 0.95 DNM1 (0.46) DEGS1LPAR3PLA2G4ASLC6A5PLA2G2C
SCHEMBL16099935 0.95 DNM1 (0.46) DEGS1LPAR3PLA2G4ASLC6A5PLA2G2C
SCHEMBL28397254 0.94 PLA2G2C (0.50) SLC6A5PLA2G2CFAAHKMT2A
SCHEMBL28397912 0.91 PLA2G2C (0.48) PLA2G2CFAAHKMT2A
SCHEMBL10081362 0.88 DNM1 (0.46) DNM1DGKAPRKCEPRKCQPRKCD
SCHEMBL15149519 0.87 DNM1 (0.51) LPAR3DNM1DGKAPRKCEPRKCQ
SCHEMBL15149657 0.87 DNM1 (0.51) LPAR3DNM1DGKAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968149-B1 PROCESS FOR FORMULATING AN ANIONIC AGENT DICERNA PHARMACEUTICALS INC (US) 2024-05-08 EP disclosed
US-20220305130-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT NOVO NORDISK A/S (DK) 2022-09-29 US disclosed
US-11351265-B2 Process for formulating an anionic agent DICERNA PHARMACEUTICALS, INC. (US) 2022-06-07 US disclosed
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS, INC. 2021-09-23 US disclosed
US-11059807-B2 Amine cationic lipids and uses thereof DICERNA PHARMACEUTICALS, INC. (US) 2021-07-13 US disclosed
EP-2768958-B1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS INC (US) 2019-08-14 EP disclosed
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT DICERNA PHARMACEUTICALS, INC. (US) 2019-05-23 US disclosed
US-20190084965-A1 AMINE CATIONIC LIPIDS AND USES THEREOF NOVO NORDISK A/S (DK) 2019-03-21 US disclosed
US-10144725-B2 Amine cationic lipids and uses thereof DICERNA PHARMACEUTICALS, INC. (US) 2018-12-04 US disclosed
US-10137201-B2 Process for formulating an anionic agent DICERNA PHARMACEUTICALS, INC. (US) 2018-11-27 US disclosed
US-20170137409-A1 Amine Cationic Lipids and Uses Thereof NOVO NORDISK A/S (DK) 2017-05-18 US disclosed
US-9549983-B2 Amine cationic lipids and uses thereof DICERNA PHARMACEUTICALS, INC. (US) 2017-01-24 US disclosed
EP-2968149-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT Dicerna Pharmaceuticals, Inc. (US) 2016-01-20 EP disclosed
US-20150374842-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT NOVO NORDISK A/S (DK) 2015-12-31 US disclosed
US-20140371293-A1 Amine Cationic Lipids and Uses Thereof DICERNA PHARMACEUTICALS, INC. (US) 2014-12-18 US disclosed
WO-2014153163-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT DICERNA PHARMACEUTICALS, INC. (US) 2014-09-25 WO disclosed
EP-2768958-A1 AMINE CATIONIC LIPIDS AND USES THEREOF Dicerna Pharmaceuticals Inc. (US) 2014-08-27 EP disclosed
WO-2013059496-A1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS, INC. (US) 2013-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190084965-A1 AMINE CATIONIC LIPIDS AND USES THEREOF SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885
US-11351265-B2 Process for formulating an anionic agent PHOSPHO1, POLRMT, LIPA DEGS1 413/4885LPAR3 152/4885PLA2G4A 297/4885
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA DEGS1 413/4885LPAR3 152/4885PLA2G4A 297/4885
US-10137201-B2 Process for formulating an anionic agent PHOSPHO1, POLRMT, LIPA DEGS1 413/4885LPAR3 152/4885PLA2G4A 297/4885
US-20220305130-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA DEGS1 413/4885LPAR3 152/4885PLA2G4A 297/4885
US-10144725-B2 Amine cationic lipids and uses thereof SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885
US-11059807-B2 Amine cationic lipids and uses thereof SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885
US-20150374842-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA DEGS1 413/4885LPAR3 152/4885PLA2G4A 297/4885
US-20140371293-A1 Amine Cationic Lipids and Uses Thereof SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885
US-20170137409-A1 Amine Cationic Lipids and Uses Thereof SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF SGMS2, SLC43A1, SGMS1 DEGS1 610/4885LPAR3 17/4885PLA2G4A 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.