Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391826 | 0.89 | FBP1 (0.45) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL28391823 | 0.87 | MEN1 (0.39) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL28959134 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL20743496 | 0.84 | ALDH1A1 (0.37) | L3MBTL1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28888834 | 0.83 | MEN1 (0.53) | L3MBTL1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL20743939 | 0.83 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28397669 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL28397631 | 0.83 | MEN1 (0.42) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL28395679 | 0.81 | MEN1 (0.41) | MEN1KMT2AALDH1A1CYP1A2GAA | |
| SCHEMBL28394165 | 0.80 | MEN1 (0.40) | L3MBTL1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601810-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-110997682-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-04-10 | — | — | CN | disclosed |