Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422953 | 0.87 | MAPT (0.61) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL8474460 | 0.87 | MAPT (0.60) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL20179117 | 0.86 | MAPT (0.60) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL10685516 | 0.83 | PPID (0.63) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL15709727 | 0.82 | LMNA (0.62) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL14450265 | 0.81 | MAPT (0.60) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL9181995 | 0.81 | SMN1; SMN2 (0.79) | MAPTLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL68851 | 0.80 | CYP4Z1 (0.62) | MAPTLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL2636023 | 0.79 | MAPT (0.60) | MAPTLMNASMN1; SMN2MEN1HTT | |
| SCHEMBL10686887 | 0.79 | MAPT (0.58) | MAPTLMNASMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171067-A | Preparation method of indole or aniline borate | 南京大学 | 2020-05-19 | — | — | CN | disclosed |