Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683652 | 0.87 | SMN1; SMN2 (0.78) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL9182180 | 0.84 | RAB9A (0.72) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL9182263 | 0.82 | NR1H4 (0.76) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL28397907 | 0.81 | MAPT (0.65) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL11361119 | 0.78 | MAPT (0.65) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL9181194 | 0.77 | RAB9A (0.76) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL17735576 | 0.76 | NPC1 (0.53) | SMN1; SMN2LMNAMEN1KMT2ARAB9A | |
| SCHEMBL10685516 | 0.76 | PPID (0.63) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL17653809 | 0.76 | LMNA (0.62) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL4920477 | 0.76 | MAPT (0.68) | SMN1; SMN2MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |