Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164111 | 0.77 | RIPK1 (0.48) | LMNARIPK1AOC3SLC6A4CYP3A4 | |
| Alcohol SCHEMBL10526338 | 0.75 | LMNA (0.48) | LMNARIPK1AOC3MEN1KMT2A | |
| SCHEMBL30387499 | 0.73 | AOC3 (0.45) | LMNAAOC3MEN1KMT2ASLC6A4 | |
| SCHEMBL27968373 | 0.71 | AOC3 (0.48) | LMNARIPK1AOC3SLC6A4CYP3A4 | |
| SCHEMBL414520 | 0.71 | LMNA (0.43) | LMNARIPK1AOC3MEN1KMT2A | |
| SCHEMBL23172374 | 0.71 | AOC3 (0.47) | LMNAAOC3MEN1KMT2ASLC6A4 | |
| SCHEMBL7434679 | 0.71 | AOC3 (0.47) | LMNAAOC3MEN1KMT2ASLC6A4 | |
| SCHEMBL4372186 | 0.71 | AOC3 (0.47) | LMNAAOC3MEN1KMT2ASLC6A4 | |
| SCHEMBL5555081 | 0.69 | RIPK1 (0.58) | LMNARIPK1AOC3NPC1 | |
| SCHEMBL11929876 | 0.69 | LMNA (0.42) | LMNARIPK1AOC3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094243-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华炎症研究公司 | 2020-05-01 | — | — | CN | disclosed |