Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL28103478 | 1.00 | CES2 (0.50) | CES2CES1CA1MAPT | |
| L-Lactic Acid SCHEMBL28087288 | 0.98 | CA1 (0.48) | CES2CES1CA1 | |
| L-Lactic Acid SCHEMBL27627039 | 0.90 | FABP3 (0.60) | MAPT | |
| L-Lactic Acid SCHEMBL31490928 | 0.84 | FFAR3 (0.44) | CES2CES1CA1 | |
| L-Lactic Acid SCHEMBL27740901 | 0.83 | CA1 (0.58) | CES2CES1CA1 | |
| Stearic Acid SCHEMBL6652003 | 0.82 | CA1 (0.61) | CES2CES1CA1 | |
| Stearic Acid SCHEMBL6654230 | 0.82 | FABP3 (0.58) | CES2CES1CA1 | |
| Octanoic Acid SCHEMBL526185 | 0.82 | FABP3 (0.58) | CES2CES1CA1 | |
| Octanoic Acid SCHEMBL526187 | 0.82 | FABP3 (0.58) | CES2CES1CA1 | |
| Stearic Acid SCHEMBL28189381 | 0.82 | FABP3 (0.58) | CES2CES1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072471-B | Preparation method of fatty acyl lactic acid or salt thereof | 中国日用化学研究院有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-111072471-A | Preparation method of fatty acyl lactic acid or salt thereof | 中国日用化学研究院有限公司 | 2020-04-28 | — | — | CN | disclosed |