SCHEMBL283985

SCHEMBL283985

CN(C)Cc1cccc2[nH]nnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP2D6 P10635 3/20 0.41
KDM4E B2RXH2 2/20 0.41
TSHR P16473 2/20 0.41
MEN1 O00255 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTR2A P28223 2/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A4 P31645 9/20 0.34
SLC6A2 P23975 8/20 0.34
MAPT P10636 1/20 0.34
MPO P05164 1/20 0.34
LMNA P02545 2/20 0.33
NPY1R P25929 1/20 0.33
MAPK1 P28482 1/20 0.33
NPY2R P49146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30080124 1.00 CYP3A4 (0.41) CYP3A4ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL284673 0.83 MAPT (0.44) ALDH1A1CYP2D6KDM4ETSHRMEN1
SCHEMBL283998 0.83 HTR2A (0.44) HTR2AHTR2CHTR2BSLC6A2TERT
SCHEMBL3462446 0.83 TAAR1 (0.40) ALDH1A1KDM4EMEN1KMT2AHSD17B10
SCHEMBL10874249 0.82 PARP1 (0.31)
SCHEMBL8511224 0.81 HRH3 (0.35) CYP3A4ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL29466093 0.80 GABRA1 (0.39) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL284553 0.80 GABRA1 (0.39) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL11313138 0.80
SCHEMBL11324942 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020019593-A1 ACIDIZING LIQUID FOR CORRODING CLAY MINERALS AND PREPARATION METHOD THEREFOR 中国石油大学(华东) 2020-01-30 WO claimed
CN-107418548-B Pyridine derivative and Mannich base composite high-temperature acidizing corrosion inhibitor 中国石油集团渤海钻探工程有限公司 2020-07-31 CN disclosed
WO-2020019593-A1 ACIDIZING LIQUID FOR CORRODING CLAY MINERALS AND PREPARATION METHOD THEREFOR 中国石油大学(华东) 2020-01-30 WO disclosed
EP-2471896-B1 REFRIGERANT OIL FOR FREEZERS AND OPERATING FLUID COMPOSITION FOR FREEZERS JX NIPPON OIL & ENERGY CORP (JP) 2017-05-24 EP disclosed
US-9090806-B2 Refrigerant oil for freezers and operating fluid composition for freezers JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-07-28 US disclosed
US-8889031-B2 Working fluid composition for refrigerator machine and refrigerating machine oil JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-11-18 US disclosed
EP-2740784-A1 Refrigerant oil for freezers and operating fluid composition for freezers JX Nippon Oil & Energy Corporation (JP) 2014-06-11 EP disclosed
EP-2733192-A1 Refrigerant oil for freezers and operating fluid composition for freezers JX Nippon Oil & Energy Corporation (JP) 2014-05-21 EP disclosed
EP-2423297-B1 Hydraulic oil composition NIPPON OIL CORP (JP) 2013-06-05 EP disclosed
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
EP-2039746-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION Nippon Oil Corporation (JP) 2009-03-25 EP disclosed
US-20080058235-A1 Lubricative Composition for Industrial Machinery and Equipment NIPPON OIL CORPORATION (JP) 2008-03-06 US disclosed
US-20070275865-A1 Refrigerating Machine Oil NIPPON OIL CORPORATION (JP) 2007-11-29 US disclosed
US-20070257229-A1 Refrigerating Machine Oil Composition NIPPON OIL CORPORATION (JP) 2007-11-08 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1734103-A1 LUBRICATING OIL COMPOSITION FOR INDUSTRIAL MACHINERY AND EQUIPMENT Nippon Oil Corporation (JP) 2006-12-20 EP disclosed
US-5912212-A OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS NIPPON OIL CO., LTD. (JP) 1999-06-15 US disclosed
EP-0781834-A2 Lubricating oil composition NIPPON OIL CO. LTD. (JP) 1997-07-02 EP disclosed
EP-0205398-A1 Additive for functional fluids CIBA-GEIGY AG (CH) 1986-12-17 EP disclosed
US-4522785-A Dialkylaminomethyl aromatic triazoles as corrosion inhibitors THE SHERWIN-WILLIAMS COMPANY (US) 1985-06-11 US disclosed