SCHEMBL3462446

SCHEMBL3462446

CN(Cc1cccc2[nH]nnc12)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.40
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
HSD17B3 P37058 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GRM5 P41594 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933280 0.85 TAAR1 (0.37) TAAR1
SCHEMBL4919621 0.85 CYP2D6 (0.34) TAAR1MEN1KMT2AKDM4ELMNA
SCHEMBL283985 0.83 CYP3A4 (0.41) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL30080124 0.83 CYP3A4 (0.41) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL534981 0.78 TRPM8 (0.38) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL284673 0.77 MAPT (0.44) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL10874249 0.76 PARP1 (0.31)
SCHEMBL8511224 0.75 HRH3 (0.35) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29466093 0.74 GABRA1 (0.39) TAAR1MEN1KMT2AKDM4EALDH1A1
SCHEMBL284553 0.74 GABRA1 (0.39) TAAR1MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed