Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | SDHA | P31040 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CALML3 | P27482 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841211 | 1.00 | TOP2B (0.47) | TOP2BMAOAMAOBPTGS1SDHA | |
| SCHEMBL3053054 | 1.00 | TOP2B (0.47) | TOP2BMAOAMAOBPTGS1SDHA | |
| SCHEMBL2838556 | 0.93 | MAOA (0.40) | TOP2BMAOAMAOBPTGS1SDHA | |
| SCHEMBL2843682 | 0.93 | MAOA (0.40) | TOP2BMAOAMAOBPTGS1SDHA | |
| SCHEMBL2845832 | 0.88 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL2841933 | 0.88 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL3063470 | 0.87 | TOP2B (0.35) | TOP2BMAOBLMNA | |
| SCHEMBL2844562 | 0.87 | TOP2B (0.35) | TOP2BMAOBLMNA | |
| SCHEMBL2841950 | 0.87 | TOP2B (0.35) | TOP2BMAOBLMNA | |
| SCHEMBL2837771 | 0.87 | KCNH2 (0.36) | MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256120-A1 | Oxazolidinone-quinolone hybrids as antibacterial compounds | Actelion Pharmaceuticals Ltd. (CH) | 2010-12-01 | — | — | EP | disclosed |