Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063470 | 1.00 | TOP2B (0.35) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2844562 | 1.00 | TOP2B (0.35) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2837771 | 0.92 | KCNH2 (0.36) | KDM4EALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL2843715 | 0.92 | KCNH2 (0.36) | KDM4EALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL2531151 | 0.92 | CALML3 (0.34) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL584990 | 0.92 | CALML3 (0.34) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2526650 | 0.89 | STAT3 (0.33) | KDM4EALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL3062421 | 0.87 | HDAC3 (0.32) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL3062417 | 0.87 | HDAC3 (0.32) | TOP2BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2840110 | 0.87 | HDAC3 (0.31) | KDM4EALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256120-A1 | Oxazolidinone-quinolone hybrids as antibacterial compounds | Actelion Pharmaceuticals Ltd. (CH) | 2010-12-01 | — | — | EP | disclosed |
| US-20100222302-A1 | Novel Antibacterial Compounds | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222302-A1 | Novel Antibacterial Compounds | ODC1, AOC1, OGFOD1 | TOP2B 4842/4885KDM4E 2548/4885ALDH1A1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.