Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Diisopentoxybenzene SCHEMBL2846102 | 0.91 | TDP1 (0.79) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL24482993 | 0.89 | NQO1 (0.58) | TDP1NQO1MAPK1EPHX2SMN1; SMN2 | |
| SCHEMBL2841624 | 0.87 | TDP1 (0.68) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| 1-Isopentyloxy-3-Ethoxybenzene SCHEMBL2840066 | 0.84 | MAPK1 (0.53) | TDP1MAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL5023581 | 0.83 | TDP1 (0.63) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| 1-Isopentyloxy-4-Methoxybenzene SCHEMBL2848524 | 0.83 | TDP1 (0.68) | TDP1MAPK1EPHX2GAAHTT | |
| SCHEMBL2926534 | 0.83 | TDP1 (0.68) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL4390750 | 0.81 | TDP1 (0.66) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL11951590 | 0.81 | TDP1 (0.71) | TDP1MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL2566452 | 0.81 | TDP1 (1.00) | TDP1MAPK1EPHX2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | SIMON FRASER UNIVERSITY (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2010-06-24 | — | — | US | disclosed |
| CN-100389133-C | Catalyst for olefin polymerization and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2008-05-21 | — | — | CN | disclosed |
| CN-1297526-C | Asymmetric diether compound and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2007-01-31 | — | — | CN | disclosed |
| CN-1769255-A | Asymmetric diether compound and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2006-05-10 | — | — | CN | disclosed |
| CN-1765941-A | Catalyst for olefin polymerization and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2006-05-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1624/4885NQO1 4260/4885MAPK1 4515/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1252/4885NQO1 4357/4885MAPK1 4550/4885 |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | CDV3, ETV1, TMSB4X | TDP1 3110/4885NQO1 3305/4885MAPK1 4482/4885 |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1255/4885NQO1 4354/4885MAPK1 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.