Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122338 | 0.79 | TP53 (0.43) | TP53CALM1ALDH1A1TSHREPHX2 | |
| SCHEMBL28400181 | 0.78 | CALM1 (0.45) | TP53CALM1ALDH1A1TSHREPHX2 | |
| SCHEMBL9007220 | 0.78 | TP53 (0.48) | TP53CALM1ALDH1A1TSHRIDO1 | |
| SCHEMBL1357485 | 0.78 | TSHR (0.48) | TP53CALM1ALDH1A1TSHRIDO1 | |
| SCHEMBL29637107 | 0.76 | TP53 (0.46) | TP53CALM1ALDH1A1TSHRIDO1 | |
| Hydrochloric Acid SCHEMBL30473262 | 0.76 | TSHR (0.46) | TP53CALM1ALDH1A1TSHRIDO1 | |
| Bromide SCHEMBL8601709 | 0.76 | TSHR (0.46) | TP53CALM1ALDH1A1TSHRIDO1 | |
| SCHEMBL1321 | 0.75 | CALM1 (0.47) | TP53CALM1ALDH1A1TSHREPHX2 | |
| Bromide SCHEMBL31215166 | 0.74 | TSHR (0.43) | TP53CALM1ALDH1A1TSHRIDO1 | |
| SCHEMBL7602162 | 0.74 | TSHR (0.43) | TP53CALM1ALDH1A1TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743059-B1 | Antibacterial oral composition for applying to dental implant areas | COLGATE PALMOLIVE CO (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6096293-A | APPLYING ORAL COMPOSITION CONTAINING 2,4-DI-TERT-BUTYL PHENOL TO TEETH | COLGATE-PALMOLIVE COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0676948-B1 | ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION | COLGATE PALMOLIVE CO (US) | 2000-06-21 | — | — | EP | disclosed |
| US-5912274-A | WATER INSOLUBLE NONCATIONIC ANTIBACTERIAL PHENOL CONTAINING, RELATIVE TO THE HYDROXYL GROUP, AN ALKYL OR CYCLOALKYL GROUP, PREFERABLY TERT.-BUTYL (T-BUTYL), IN THE 2-POSITION, AND SUBSTITUENTS IN ONE OR BOTH OF THE 4- AND 5-POSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0852486-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| WO-1997010800-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0743059-A2 | Process for applying antibacterial oral composition to dental implant areas | Colgate-Palmolive Company (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5575652-A | Process for applying antibacterial oral composition to dental implant areas | COLGATE PALMOLIVE COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| US-5525330-A | CONTAINING N-METHYLPYRROLIDONE ALONE OR IN COMBINATION WITHNONCATIONIC ANTIBACTERIAL AGENT | COLGATE PALMOLIVE COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0628302-A2 | Oral composition containing salicylanilide antibacterial agent | Colgate-Palmolive Company (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5368844-A | N-methylpyrrolidone | COLGATE PALMOLIVE COMPANY (US) | 1994-11-29 | — | — | US | disclosed |
| US-5275805-A | Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants | COLGATE-PALMOLIVE CO. | 1994-01-04 | — | — | US | disclosed |