Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430742 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL4948731 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| Sulfuric Acid SCHEMBL26104563 | 0.85 | LMNA (0.59) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL6114799 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| Sulfuric Acid SCHEMBL28171473 | 0.84 | LMNA (0.58) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| Sulfuric Acid SCHEMBL28171472 | 0.84 | LMNA (0.58) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL28410913 | 0.84 | LMNA (0.67) | ALDH1A1SMN1; SMN2TDP1LMNAHTT | |
| Piconol SCHEMBL8630735 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL3998241 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL4558575 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115732749-A | Composite solid electrolyte and preparation method thereof | 多氟多新材料股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-114794230-B | Chitosan/vegetable oil/polyphenol derivative and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2022-11-25 | — | — | CN | claimed |
| CN-114794230-A | Chitosan/vegetable oil/polyphenol derivative and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2022-07-29 | — | — | CN | claimed |
| CN-111974318-B | Composite defective metal organic framework gel proton conducting material and preparation method thereof | 哈尔滨师范大学 | 2022-03-22 | — | — | CN | claimed |
| CN-112142593-B | Preparation method of isobornyl (meth) acrylate of biological origin | 华南农业大学 | 2021-07-06 | — | — | CN | claimed |
| CN-112680277-A | Method for preparing sulfurized fatty acid by using kitchen waste oil | 正大国际科技(常德)集团有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112625803-A | Method for preparing higher fatty acid ester by using illegal cooking oil | 正大国际科技(常德)集团有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112142593-A | Preparation method of isobornyl (meth) acrylate of biological origin | 华南农业大学 | 2020-12-29 | — | — | CN | claimed |
| CN-111974318-A | Composite defective metal organic framework gel proton conducting material and preparation method thereof | 哈尔滨师范大学 | 2020-11-24 | — | — | CN | claimed |
| CN-107189750-B | Tung oil-based biodegradable UV (ultraviolet) curing adhesive and preparation method and application thereof | 华南农业大学 | 2020-05-15 | — | — | CN | claimed |
| CN-116285020-B | Preparation method of chitosan/phenolic acid composite coating film | 中国热带农业科学院农产品加工研究所 | 2023-11-03 | — | — | CN | disclosed |
| CN-116285020-A | Preparation method of chitosan/phenolic acid composite coating film | 中国热带农业科学院农产品加工研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-114794231-B | Chitosan plant essential oil microcapsule composite coating preservative and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2023-03-21 | — | — | CN | disclosed |
| CN-115732749-A | Composite solid electrolyte and preparation method thereof | 多氟多新材料股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-114794230-B | Chitosan/vegetable oil/polyphenol derivative and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2022-11-25 | — | — | CN | disclosed |
| CN-112142593-B | Preparation method of isobornyl (meth) acrylate of biological origin | 华南农业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-112680277-A | Method for preparing sulfurized fatty acid by using kitchen waste oil | 正大国际科技(常德)集团有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-112625803-A | Method for preparing higher fatty acid ester by using illegal cooking oil | 正大国际科技(常德)集团有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112142593-A | Preparation method of isobornyl (meth) acrylate of biological origin | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107189750-B | Tung oil-based biodegradable UV (ultraviolet) curing adhesive and preparation method and application thereof | 华南农业大学 | 2020-05-15 | — | — | CN | disclosed |