Phosphoric Acid

Phosphoric Acid

SCHEMBL28401200

N.O=P(O)(O)O.OCC(CO)(CO)CO

nearest known ligand 0.37

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.33
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TYMS P04818 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5467110 1.00 ALDH1A1 (0.37) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL135754 0.96 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL7695631 0.96 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL133397 0.96 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL7139936 0.96 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL23777274 0.96 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL27941976 0.93 ALDH1A1 (0.37) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL9561741 0.87 TSHR (0.36) ALDH1A1TSHRKDM4EMMP2THRB
Phosphoric Acid SCHEMBL5086299 0.87 FDPS (0.38) ALDH1A1TSHR
Phosphoric Acid SCHEMBL6270604 0.87 TSHR (0.36) ALDH1A1TSHRKDM4EMMP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111118893-A Flame-retardant method for cotton fabric 盐城工学院 2020-05-08 CN disclosed