Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825297 | 1.00 | LMNA (0.40) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL13829622 | 1.00 | LMNA (0.40) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL6296060 | 0.79 | LMNA (0.36) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL701888 | 0.79 | RORC (0.34) | TSHRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12095052 | 0.79 | RORC (0.34) | TSHRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL92811 | 0.77 | TSHR (0.50) | TSHRCHRM2CHRM4CHRM1MAPT | |
| SCHEMBL12095053 | 0.77 | TSHR (0.32) | TSHRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5665771 | 0.77 | LMNA (0.41) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL16987582 | 0.77 | LMNA (0.41) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL8760081 | 0.77 | TSHR (0.50) | TSHRCHRM2CHRM4CHRM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698009-A | CD73 inhibiting 2,4-dioxopyrimidine compounds | 吉利德科学公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |