Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23431347 | 0.84 | NPSR1 (0.44) | MAPTHTTNPSR1GPR3KDM4E | |
| SCHEMBL28400804 | 0.79 | NR4A2 (0.43) | HPGDGAAL3MBTL1POLBNPC1 | |
| SCHEMBL12792049 | 0.78 | NPSR1 (0.40) | MAPTLMNAHPGDNPSR1GPR3 | |
| SCHEMBL28404959 | 0.77 | ALDH1A1 (0.38) | HTTLMNAHPGDTSHRNPSR1 | |
| SCHEMBL16447094 | 0.75 | NPSR1 (0.42) | MAPTHTTLMNAHPGDNPSR1 | |
| SCHEMBL12792062 | 0.74 | NPSR1 (0.40) | MAPTHTTHPGDTSHRNPSR1 | |
| SCHEMBL13781018 | 0.74 | KDM4E (0.50) | MAPTHTTLMNAHPGDTSHR | |
| SCHEMBL12150652 | 0.71 | GPR3 (0.46) | MAPTHTTLMNAHPGDNPSR1 | |
| SCHEMBL801108 | 0.70 | NPSR1 (0.44) | MAPTHTTLMNAHPGDTSHR | |
| SCHEMBL23911727 | 0.70 | KDM4E (0.46) | MAPTLMNAHPGDNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-B | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | disclosed |