Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401361 | 0.77 | MAPT (0.46) | ALDH1A1KDM4EHTTNPSR1RXFP1 | |
| SCHEMBL15451810 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTPPARGNPSR1 | |
| SCHEMBL13183691 | 0.72 | GPR3 (0.47) | ALDH1A1KDM4EHTTHSD17B10TSHR | |
| SCHEMBL21032290 | 0.70 | ALDH1A1 (0.35) | ALDH1A1KDM4EHTTPPARGNPSR1 | |
| SCHEMBL26050220 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTTPPARGNPSR1 | |
| SCHEMBL14652688 | 0.69 | MEN1 (0.38) | ALDH1A1KDM4ESMN1; SMN2GAAHSD17B10 | |
| SCHEMBL19038262 | 0.69 | JAK2 (0.37) | ALDH1A1KDM4ESMN1; SMN2GAAHSD17B10 | |
| SCHEMBL18435677 | 0.69 | AHR (0.36) | ALDH1A1KDM4ESMN1; SMN2GAAHSD17B10 | |
| SCHEMBL18646553 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTTPPARGNPSR1 | |
| SCHEMBL21781234 | 0.69 | GPR3 (0.43) | ALDH1A1KDM4EHTTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-B | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | disclosed |