Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400051 | 0.83 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11691275 | 0.81 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11092126 | 0.79 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL22769590 | 0.76 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL28399151 | 0.75 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL28398391 | 0.75 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL7487086 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11558486 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11505491 | 0.73 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11688249 | 0.72 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004164-B | Preparation method of polysubstituted 2-aryl indole derivative | 浙江工业大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-111004164-A | Preparation method of polysubstituted 2-aryl indole derivative | 浙江工业大学 | 2020-04-14 | — | — | CN | disclosed |