Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686979 | 0.89 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11691275 | 0.88 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL17674338 | 0.85 | L3MBTL1 (0.77) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL28400051 | 0.84 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL22769590 | 0.83 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11505491 | 0.80 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11558486 | 0.80 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4651300 | 0.79 | KDM4E (0.61) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL11688249 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL28401787 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444684-A | Azo dyes containing a diazotized 5-amino isothiazol moiety having thereon a sulfonic acid or salt group | EASTMAN KODAK COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4419290-A | COLORFASTNESS | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-06 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3956267-A | Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |