Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153285 | 1.00 | LMNA (0.57) | LMNAMEN1TSHRKMT2ACRACR2A | |
| SCHEMBL28407306 | 0.85 | POLB (0.52) | LMNARAB9ANPC1CYP3A4ALDH1A1 | |
| SCHEMBL28401527 | 0.84 | CRACR2A (0.51) | CRACR2ABRAFTRPA1KCNT1CYP3A4 | |
| SCHEMBL30153261 | 0.82 | STIM1 (0.50) | CRACR2ARAB9ABRAFCYP3A4KDM4E | |
| SCHEMBL28398093 | 0.82 | STIM1 (0.50) | CRACR2ARAB9ABRAFCYP3A4KDM4E | |
| SCHEMBL28399748 | 0.82 | LMNA (0.62) | LMNAMEN1TSHRKMT2ARAB9A | |
| SCHEMBL28401280 | 0.81 | KDM4E (0.55) | LMNAMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL30153256 | 0.81 | KCNK3 (0.56) | LMNAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28393670 | 0.81 | KCNK3 (0.56) | LMNAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28401432 | 0.80 | GRM5 (0.51) | LMNAMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187215-B | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |