Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CKS1B | P61024 | 4/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057275 | 1.00 | NAMPT (0.53) | NAMPTLMNAMCOLN3CA12CA2 | |
| SCHEMBL23057287 | 0.86 | LMNA (0.71) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL28402292 | 0.86 | NAMPT (0.60) | NAMPTLMNAMCOLN3CA12CA2 | |
| SCHEMBL31720637 | 0.77 | KCNA5 (0.56) | NAMPTLMNAALDH1A1KDM4EKCNA5 | |
| SCHEMBL28455396 | 0.77 | SLC22A12 (0.67) | NAMPTCKS1BSKP2PTGS2ALDH1A1 | |
| SCHEMBL30936619 | 0.73 | MCOLN2 (0.51) | LMNAALDH1A1L3MBTL1USP2POLB | |
| SCHEMBL7370367 | 0.73 | CKS1B (0.53) | NAMPTLMNAMCOLN3CA12CA2 | |
| SCHEMBL6691608 | 0.72 | MEN1 (0.52) | NAMPTCA12CA2CA9CKS1B | |
| SCHEMBL23043640 | 0.72 | MCOLN2 (0.50) | LMNACA2CA9ALDH1A1L3MBTL1 | |
| SCHEMBL23057210 | 0.72 | KEAP1 (0.51) | LMNAALDH1A1L3MBTL1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | NAMPT 877/4885LMNA 581/4885MCOLN3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.