Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614134 | 1.00 | PPM1B (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL20489196 | 1.00 | PPM1B (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL16405665 | 1.00 | PPM1B (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL34472936 | 0.92 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL34468392 | 0.87 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL32677632 | 0.81 | PPM1B (0.44) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL32677631 | 0.81 | PPM1B (0.44) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL15712143 | 0.80 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL23780231 | 0.78 | — | — | |
| SCHEMBL5778032 | 0.78 | PPM1B (0.43) | PPM1BPTPN1PPP1CCMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892684-B | Quinazoline derivatives, pharmaceutical compositions thereof, and use as medicaments | 锦州奥鸿药业有限责任公司 | 2020-05-26 | — | — | CN | disclosed |