Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677631 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL1867430 | 0.81 | LMNA (0.42) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL16405665 | 0.81 | PPM1B (0.49) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL28403234 | 0.81 | PPM1B (0.49) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL1614134 | 0.81 | PPM1B (0.49) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL20489196 | 0.81 | PPM1B (0.49) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL34472936 | 0.78 | PPM1B (0.46) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL13085057 | 0.75 | LMNA (0.40) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL17904756 | 0.75 | LMNA (0.40) | PPM1BPTPN1PPP1CCLMNAALDH1A1 | |
| SCHEMBL15712143 | 0.74 | PPM1B (0.53) | PPM1BPTPN1PPP1CCLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026041636-A1 | MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2026-02-26 | — | — | WO | disclosed |