Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenoxazine SCHEMBL27280590 | 0.82 | MAPT (0.65) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2774415 | 0.79 | ALOX5 (0.57) | MAPTKMT2AMEN1POLBALDH1A1 | |
| Bromide SCHEMBL2778445 | 0.77 | ALOX5 (0.55) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28424272 | 0.77 | ALDH1A1 (0.43) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28405071 | 0.77 | SNCA (0.59) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2043484 | 0.75 | ALOX5 (0.53) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL29636451 | 0.75 | MAPT (0.72) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL30811587 | 0.75 | MAPT (0.72) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL21628256 | 0.75 | MAPT (0.72) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9093133 | 0.75 | ALOX5 (0.50) | MAPTKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087360-A | Diamine with novel structure and preparation method and application thereof | 湖南工业大学 | 2020-05-01 | — | — | CN | disclosed |