Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277361 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL15669931 | 0.68 | MAPT (0.48) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| Methane SCHEMBL11336749 | 0.68 | MAPT (0.48) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL1895535 | 0.68 | MAPT (0.48) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL1894049 | 0.68 | MAPT (0.48) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL7898627 | 0.68 | MAPT (0.48) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL31738422 | 0.65 | TDP1 (0.66) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL19955179 | 0.65 | TDP1 (0.66) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL395878 | 0.65 | TDP1 (0.66) | ALDH1A1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL5729305 | 0.65 | CFTR (1.00) | CFTRGOPCALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043459-A | Chemically modified oligonucleotides | 菲奥医药公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-108884054-B | Compounds for the treatment of proliferative diseases | 儿童医学中心公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114533900-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114206389-A | Multivalent ligand clusters for targeted delivery of therapeutic agents | 有丝分裂疗法有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113956315-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-108137492-B | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-107936076-B | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-113278617-A | Chiral design | 波涛生命科学有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-113234114-A | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-106068325-B | Chiral design | 波涛生命科学有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-108976272-B | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112057457-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-111936136-A | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106793775-B | Dihydropyrazinone derivatives and uses thereof | 达纳-法伯癌症研究所股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111163771-A | Use of pyrimidopyrimidinones as SIK inhibitors | 通用医疗公司 | 2020-05-15 | — | — | CN | disclosed |