SCHEMBL28403585

SCHEMBL28403585

CCc1ccc(C(=O)OC(=O)c2ccc(CC)c(CC)c2)cc1CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
ALDH1A1 P00352 3/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
ESR1 P03372 2/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
HSD17B2 P37059 1/20 0.39
PLK1 P53350 1/20 0.38
XDH P47989 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28403587 0.91 LMNA (0.47) ALDH1A1KMT2ASMN1; SMN2HIF1ALMNA
SCHEMBL28399314 0.89 PPARG (0.43) CA12CA1CA2CA7CA9
SCHEMBL28398118 0.89 PPARG (0.46) CA12CA1CA2CA7CA9
SCHEMBL27279304 0.86 CA1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL28407107 0.86 TYR (0.42) ALDH1A1ESR1RECQLSMN1; SMN2PLK1
SCHEMBL28401251 0.86 ALOX15 (0.37) CA12CA1CA2CA7CA9
SCHEMBL27792549 0.84 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL28401900 0.84 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL28403107 0.82 PPARG (0.44) CA12CA1CA2CA7CA9
SCHEMBL10886320 0.81 ALDH1A1 (0.53) ALDH1A1HSP90AA1HSP90AB1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN claimed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN disclosed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN disclosed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed