Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404929 | 1.00 | SLC2A1 (0.56) | SLC2A1TDP1SRD5A2P4HTMMEN1 | |
| SCHEMBL20337186 | 0.81 | SLC2A1 (0.59) | SLC2A1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL14988861 | 0.78 | MAPT (0.56) | SLC2A1MEN1KMT2ACYP1B1PIM1 | |
| SCHEMBL14988862 | 0.78 | MAPT (0.56) | SLC2A1MEN1KMT2ACYP1B1PIM1 | |
| SCHEMBL9000418 | 0.77 | SLC2A1 (0.58) | SLC2A1MEN1KMT2ACYP1A2GAA | |
| SCHEMBL28404135 | 0.76 | POLB (0.52) | SLC2A1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2947694 | 0.75 | TDP1 (0.61) | TDP1SRD5A2P4HTMMEN1KMT2A | |
| SCHEMBL20464764 | 0.75 | SLC2A1 (0.56) | SLC2A1MEN1KMT2APIM1NPC1 | |
| SCHEMBL9000735 | 0.75 | P4HA1 (0.52) | P4HTMMEN1KMT2AP4HA1CYP1A2 | |
| SCHEMBL286351 | 0.74 | SLC2A1 (0.64) | SLC2A1MEN1KMT2ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524053-B | Tetrahydrobenzothiophene compounds | 广东东阳光药业有限公司 | 2020-06-05 | — | — | CN | disclosed |