Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167189 | 0.89 | ALDH1A1 (0.84) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL8062381 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDNPC1LMNAKDM4E | |
| SCHEMBL14934861 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDSCN3AKMT2ANPC1 | |
| SCHEMBL1844542 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL6206231 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL6206225 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL28414245 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ANPC1KDM4E | |
| SCHEMBL28407968 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ANPC1KDM4E | |
| SCHEMBL31530561 | 0.76 | ALDH1A1 (0.65) | ALDH1A1HPGDSCN3AKMT2ANPC1 | |
| SCHEMBL12531247 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HPGDSCN3AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269203-A | N-cyclohexyl-furan-2-formamide compound and preparation method and application thereof | 上海中泽医药科技有限公司 | 2020-06-12 | — | — | CN | disclosed |