Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531247 | 0.91 | ALDH1A1 (0.64) | ALDH1A1HPGDUTS2RKMT2ANPC1 | |
| SCHEMBL4167189 | 0.89 | ALDH1A1 (0.84) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL11463346 | 0.88 | ALDH1A1 (0.57) | ALDH1A1HPGDUTS2RKMT2ANPC1 | |
| SCHEMBL8062381 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDNPC1LMNAKDM4E | |
| SCHEMBL28404651 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL14934861 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL13837808 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDUTS2REPHX1GAA | |
| SCHEMBL6206231 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL6206225 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2ANPC1LMNA | |
| SCHEMBL28407968 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325183-A1 | 4-(2-Furoyl) Aminopiperidine compound useful as therapeutic agent for itching | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-7713965-B2 | 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713965-B2 | 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2010-05-11 | — | — | US | disclosed |
| CN-100582103-C | 4-(2-furoyl)aminopiperidine compound useful as therapeutic agent for itching | KYORIN SEIYAKU KK | 2010-01-20 | — | — | CN | disclosed |
| US-7601843-B2 | 4-(2-furoyl)aminopiperidine compound useful as therapeutic agent for itching | KYORIN PHARMACEUTICAL CO., LTD (JP) | 2009-10-13 | — | — | US | disclosed |
| US-7601843-B2 | 4-(2-furoyl)aminopiperidine compound useful as therapeutic agent for itching | KYORIN PHARMACEUTICAL CO., LTD (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2009-09-03 | — | — | US | disclosed |
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2009-09-03 | — | — | US | disclosed |
| EP-1621538-A4 | 4-(2-FUROYL)AMINOPIPERIDINE COMPOUND USEFUL AS THERAPEUTIC AGENT FOR ITCHING | KYORIN SEIYAKU KK (JP) | 2009-07-29 | — | — | EP | disclosed |
| EP-1443046-B1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN SEIYAKU KK (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-20050085508-A1 | Novel 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2005-04-21 | — | — | US | disclosed |
| CN-1582286-A | Novel 4-2-furoylaminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN SEIYAKU KK (JP) | 2005-02-16 | — | — | CN | disclosed |
| CN-1582286-A | Novel 4-2-furoylaminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN SEIYAKU KK (JP) | 2005-02-16 | — | — | CN | disclosed |
| JP-2004352714-A | NEW 4-(2-FUROYL)AMINOPIPERIDINE DERIVATIVE | KYORIN PHARMACEUT CO LTD | 2004-12-16 | — | — | JP | disclosed |
| WO-2004099194-A1 | 4-(2-FUROYL)AMINOPIPERIDINE COMPOUND USEFUL AS THERAPEUTIC AGENT FOR ITCHING | KYORIN PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |
| EP-1443046-A1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-1443046-A1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-1443046-A1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003035645-A1 | NOVEL 4-(2-FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003035645-A1 | NOVEL 4-(2-FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | CBR3, CBR1, TECR | ALDH1A1 1998/4885HPGD 1022/4885UTS2R 1869/4885 |
| US-20050085508-A1 | Novel 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | OPRM1, OPRD1, HRH4 | ALDH1A1 2958/4885HPGD 1099/4885UTS2R 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.