Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28408488 | 0.99 | ACP1 (0.56) | ACP1HTR4ADRA1AKCNH2HRH3 | |
| SCHEMBL30689007 | 0.78 | ACP1 (0.55) | ACP1ADRA1AKCNH2HRH3 | |
| SCHEMBL28416153 | 0.75 | NCF1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL28059935 | 0.74 | NCF1 (0.49) | — | |
| SCHEMBL16009558 | 0.74 | KDM4E (0.56) | ACP1HRH3 | |
| SCHEMBL31492115 | 0.73 | NCF1 (0.54) | — | |
| SCHEMBL10645201 | 0.73 | NCF1 (0.54) | — | |
| SCHEMBL30367647 | 0.73 | TLR8 (0.63) | ACP1HRH3 | |
| SCHEMBL6302805 | 0.72 | ALDH1A1 (0.51) | KCNH2HRH3 | |
| SCHEMBL19260720 | 0.72 | HRH3 (0.54) | ACP1ADRA1AKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536509-B | Novel compounds as dual inhibitors of histone methyltransferase and DNA methyltransferase | 基础应用医学研究基金会 | 2020-06-09 | — | — | CN | disclosed |