Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22366521 | 0.99 | KDM4A (0.47) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL13199871 | 0.84 | KDM4A (0.47) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL18768485 | 0.83 | KDM4A (0.46) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL26703790 | 0.82 | KDM4A (0.48) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL28405232 | 0.80 | KDM4A (0.43) | KDM4ANAMPTATMKCNA5HDAC1 | |
| Iodide SCHEMBL22366402 | 0.79 | KDM4A (0.42) | KDM4ANAMPTATMKCNA5HDAC1 | |
| SCHEMBL28405237 | 0.78 | MAPT (0.41) | KDM4ANAMPTCA12CA1CA7 | |
| Iodide SCHEMBL22366399 | 0.77 | MAPT (0.41) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL30159605 | 0.76 | KCNA5 (0.56) | KDM4ANAMPTCA12CA1CA7 | |
| SCHEMBL8018113 | 0.76 | KCNA5 (0.56) | KDM4ANAMPTCA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225917-A | Substituted imidazopyridine amides and uses thereof | 拜耳股份公司 | 2020-06-02 | — | — | CN | disclosed |