Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22366402 | 0.99 | KDM4A (0.42) | KDM4APOLBL3MBTL1NAMPTMAPT | |
| SCHEMBL28405161 | 0.80 | KDM4A (0.48) | KDM4AL3MBTL1NAMPTGLSATM | |
| SCHEMBL28405237 | 0.79 | MAPT (0.41) | KDM4APOLBL3MBTL1NAMPTMAPT | |
| Iodide SCHEMBL22366521 | 0.79 | KDM4A (0.47) | KDM4AL3MBTL1NAMPTATMHDAC1 | |
| Iodide SCHEMBL22366399 | 0.78 | MAPT (0.41) | KDM4APOLBL3MBTL1NAMPTMAPT | |
| SCHEMBL10553465 | 0.77 | IDO1 (0.37) | KDM4AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5015072 | 0.74 | NPC1 (0.54) | KDM4AL3MBTL1MAPTLMNAGAA | |
| SCHEMBL15171404 | 0.72 | NPC1 (0.52) | KDM4APOLBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8279661 | 0.72 | POLB (0.53) | KDM4APOLBNAMPTMAPTGLS | |
| SCHEMBL5796279 | 0.71 | L3MBTL1 (0.56) | L3MBTL1NAMPTMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225917-A | Substituted imidazopyridine amides and uses thereof | 拜耳股份公司 | 2020-06-02 | — | — | CN | disclosed |