Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22366399 | 0.99 | MAPT (0.41) | MAPTTDP1KDM4AL3MBTL1CA1 | |
| SCHEMBL28405232 | 0.79 | KDM4A (0.43) | MAPTTDP1KDM4AL3MBTL1NAMPT | |
| SCHEMBL28405161 | 0.78 | KDM4A (0.48) | KDM4AL3MBTL1CA1CA12CA7 | |
| Iodide SCHEMBL22366402 | 0.78 | KDM4A (0.42) | MAPTTDP1KDM4AL3MBTL1NAMPT | |
| Iodide SCHEMBL22366521 | 0.77 | KDM4A (0.47) | KDM4AL3MBTL1CA1CA12CA7 | |
| SCHEMBL5796279 | 0.75 | L3MBTL1 (0.56) | MAPTTDP1L3MBTL1CA1CA2 | |
| Acetic Acid SCHEMBL8138998 | 0.72 | SMN1; SMN2 (0.53) | MAPTTDP1L3MBTL1CA1CA12 | |
| SCHEMBL5015072 | 0.72 | NPC1 (0.54) | MAPTKDM4AL3MBTL1LMNAGAA | |
| SCHEMBL3180689 | 0.71 | L3MBTL1 (0.61) | MAPTTDP1KDM4AL3MBTL1CA1 | |
| SCHEMBL15171404 | 0.71 | NPC1 (0.52) | KDM4AL3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225917-A | Substituted imidazopyridine amides and uses thereof | 拜耳股份公司 | 2020-06-02 | — | — | CN | disclosed |