Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26404933 | 0.84 | NNMT (0.45) | NNMTRIPK2TLR8ALDH1A1POLB | |
| SCHEMBL1831743 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL29153863 | 0.79 | MEN1 (0.37) | POLBSMN1; SMN2LMNA | |
| SCHEMBL20774866 | 0.79 | P2RX7 (0.31) | — | |
| SCHEMBL1992512 | 0.76 | RIPK2 (0.39) | NNMTRIPK2TLR8ALDH1A1POLB | |
| SCHEMBL5204576 | 0.75 | TSHR (0.44) | NNMTRIPK2TLR8ALDH1A1POLB | |
| SCHEMBL28889856 | 0.75 | F2 (0.41) | ALDH1A1POLBTSHRSMN1; SMN2LMNA | |
| SCHEMBL174225 | 0.73 | RIPK2 (0.51) | RIPK2TLR8ALDH1A1POLBSIRT3 | |
| SCHEMBL6397435 | 0.73 | SMN1; SMN2 (0.49) | NNMTRIPK2TLR8ALDH1A1POLB | |
| SCHEMBL17397802 | 0.72 | RIPK2 (0.39) | NNMTRIPK2TLR8ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787324-B | Process for preparing carbamoylaminopyrazole derivatives | 桑多斯股份公司 | 2020-05-19 | — | — | CN | disclosed |