Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231955 | 0.84 | LMNA (0.48) | MEN1GAAMAPTKMT2AMAOA | |
| SCHEMBL29405377 | 0.81 | PGR (0.49) | PGRPDE7AKDM4EMEN1NPC1 | |
| SCHEMBL16629748 | 0.81 | PGR (0.49) | PGRPDE7AKDM4EMEN1NPC1 | |
| SCHEMBL19566509 | 0.80 | PGR (0.43) | PGRPDE7AMAOAMAOB | |
| SCHEMBL19001732 | 0.80 | LMNA (0.51) | PGRPDE7AKDM4EMEN1NPC1 | |
| SCHEMBL15464072 | 0.79 | PGR (0.53) | PGRPDE7AKDM4EMEN1NPC1 | |
| SCHEMBL20138592 | 0.78 | PGR (0.45) | PGRPDE7AKDM4EMEN1NPC1 | |
| SCHEMBL18457636 | 0.77 | PDK2 (0.51) | PGRMEN1NPC1MAPTKMT2A | |
| SCHEMBL12109350 | 0.75 | PDK2 (0.52) | PGR | |
| SCHEMBL16389424 | 0.75 | PDK2 (0.41) | PGRPDE7AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170942-A | Preparation and application of chiral (R/S) -9-methyl-2, 9-diphenyl-9, 10-dihydroacridine derivative | 苏州大学 | 2020-05-19 | — | — | CN | claimed |
| CN-111170942-A | Preparation and application of chiral (R/S) -9-methyl-2, 9-diphenyl-9, 10-dihydroacridine derivative | 苏州大学 | 2020-05-19 | — | — | CN | disclosed |