SCHEMBL20138592

SCHEMBL20138592

c1ccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2cc(-c4ccccc4)ccc2N3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 8/20 0.45
PDE7A Q13946 1/20 0.45
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
NPC1 O15118 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
LMNA P02545 2/20 0.43
TDP2 O95551 1/20 0.38
USP2 O75604 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
HSP90AA1 P07900 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001732 0.95 LMNA (0.51) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL28367619 0.85 KDM4E (0.44) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL26027532 0.84 PGR (0.41) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL14933328 0.81 PDK2 (0.49) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL30019645 0.81 PDK2 (0.49) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL15464072 0.78 PGR (0.53) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL28405602 0.78 PGR (0.44) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL15030667 0.78 ALOX5 (0.41) PGRPDE7AKDM4EMEN1MAPT
SCHEMBL13833088 0.77 GAA (0.47) KDM4EMEN1MAPTKMT2AGAA
SCHEMBL30825149 0.77 GAA (0.47) KDM4EMEN1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-24 US disclosed
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 PGR 394/4885PDE7A 4768/4885KDM4E 2946/4885
US-20180134706-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME OR10J3, HDAC10, RBM12 PGR 1353/4885PDE7A 4247/4885KDM4E 565/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 PGR 2192/4885PDE7A 4601/4885KDM4E 1802/4885
US-10844059-B2 Heterocyclic compound and organic electroluminescence device including the same OR10J3, HDAC10, RBM12 PGR 1353/4885PDE7A 4247/4885KDM4E 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.