SCHEMBL2840569

SCHEMBL2840569

COc1cc(S(=O)(=O)O)c(I)cc1I

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
PKM P14618 2/20 0.38
MPL P40238 1/20 0.35
HTR1A P08908 2/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
HTR2B P41595 2/20 0.35
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
APP P05067 1/20 0.35
GSK3B P49841 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PMP22 Q01453 2/20 0.34
MEN1 O00255 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2844078 0.92 HTR2A (0.39) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL7934815 0.85 KMT2A (0.41) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL1888725 0.79 ALDH1A1 (0.51) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL4565243 0.76 TET2 (0.35) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL2842600 0.74 BRD4 (0.34) ALDH1A1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL481617 0.73 HTR2A (0.47) ALDH1A1LMNAMAPTHTR1AHTR2A
SCHEMBL197408 0.73 HTR2A (0.33) ALDH1A1KMT2ALMNAPKMHTR1A
SCHEMBL9774295 0.73 ALDH1A1 (0.50) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL13517582 0.72 ALDH1A1 (0.43) ALDH1A1KMT2ALMNAMAPTPKM
SCHEMBL28773157 0.72 L3MBTL1 (0.41) MAPTPKMMPLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed