Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Aziridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aziridine SCHEMBL3134345 | 1.00 | — | — | |
| Bromide SCHEMBL3966683 | 0.93 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL1005659 | 0.93 | — | — | |
| Piperazine SCHEMBL1224331 | 0.93 | — | — | |
| Bromide SCHEMBL6017046 | 0.93 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL1005658 | 0.93 | HIF1A (0.86) | — | |
| Aziridine SCHEMBL16878816 | 0.91 | — | — | |
| Aziridine SCHEMBL2267 | 0.91 | — | — | |
| Aziridine SCHEMBL3089497 | 0.91 | — | — | |
| Piperazine SCHEMBL5380983 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194226-B | Hygroscopic, crosslinked coatings and bioadhesives | 南洋理工大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-111194226-A | Hygroscopic, crosslinked coatings and bioadhesives | 南洋理工大学 | 2020-05-22 | — | — | CN | disclosed |