SCHEMBL28405771

SCHEMBL28405771

Nc1ccc2c(c1)Sc1c(N)cccc1S2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NOX1 Q9Y5S8 2/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CHRM3 P20309 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41
HTR2B P41595 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTPN5 P54829 1/20 0.39
BLM P54132 1/20 0.37
MAPT P10636 1/20 0.37
ALOX5 P09917 1/20 0.37
CYP3A4 P08684 3/20 0.34
CASP1 P29466 2/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089121 0.84 PTPN5 (0.47) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL3163268 0.82 MEN1 (0.39) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL22561858 0.82 MEN1 (0.55) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL2362637 0.82
SCHEMBL10363196 0.79 MEN1 (0.45) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL1144983 0.79 MEN1 (0.45) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL28265223 0.75 KMT2A (0.36) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL3175328 0.72 NOX1 (0.38) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL28048870 0.72 ALDH1A1 (0.39) MEN1KMT2ANOX1ADRA2AADRA2B
SCHEMBL28825592 0.71 PLA2G7 (0.38) MEN1KMT2ANOX1ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230781-A Preparation method of low molecular weight polycarbonate polyether polyol with autocatalysis effect 河北工业大学 2022-03-25 CN claimed
CN-111454451-B Preparation method of polyimide microspheres 东莞东阳光科研发有限公司 2022-12-09 CN disclosed
CN-113169418-A Polyimide microsphere slurry, composite diaphragm and lithium ion battery 东莞东阳光科研发有限公司 2021-07-23 CN disclosed
CN-109817870-B Polyimide microsphere slurry, composite diaphragm and lithium ion battery 东莞东阳光科研发有限公司 2020-06-05 CN disclosed